The CCBBI Student Group welcomes Tzu-Chen (Jane) Lung, a graduate student with Dr. Kristen Kennedy at the University of Texas at Dallas. The Student Workshop series complements the CCBBI fMRI Talk series. Each session features a trainee from seminar speaker's research group, offering CCBBI trainees a more in-depth look at current projects and methodologies.
Title: Exploring Cognitive Aging and Structure-Function Association Across the Lifespan: From Mean BOLD Signals to Longitudinal Variability Dynamics
Abstract: Age-related cognitive decline is accompanied by alterations in white matter connectivity and Blood Oxygen Level-Dependent (BOLD) signal dynamics. Across two complementary studies, we investigated the interplay between structural integrity, dynamic functional modulation, and cognitive trajectories over the adult lifespan. Study 1 examined how lifespan decline in white matter microstructure (measured by fractional anisotropy) co-occurs with task-difficulty-dependent BOLD signal modulation. Building upon these, Study 2 evaluated longitudinal changes in BOLD variability, assessing their specific coupling with Neurite Orientation Dispersion and Density Imaging (NODDI) and cognitive change.
Zoom link: https://osu.zoom.us/j/2345900971?pwd=eTMxYUsvVUthOGU2dmNqdDdodlcwUT09
