The Social & Affective Immunology Lab's research is focused on how psychological factors (e.g. stress; valence weighting bias) trigger the immune system and also how the immune system can alter emotions and decision-making. They use both pharmacological (acetaminophen; ibuprofen; typhoid vaccination) and endogenous measures (e.g. C-Reactive Protein) of immune function. They are also conducting a large, longitudinal imaging study of adolescents to look at how geospatial stress exposure alters neural activity and predicts future substance use.