The Voice and Resonance Laboratory team is working towards understanding the anatomic, physiologic, and acoustic aspects of the normal and abnormal speech production mechanism, with special emphasis on the velopharyngeal mechanism, through combining bio-imaging techniques and acoustic analysis methods.
Bae, Y., & Pfeil , G. (2018). Structural changes following velopharyngeal resistance training (continuous positive airway pressure therapy): A preliminary report. Cleft Palate-Craniofacial Journal, 55, 1321-1328. doi: 10.1177/1055665618758694
The Beauchaine Lab studies how temperamental predispositions, such as behavioral impulsivity develop, and how socialization of emotion regulation can protect against temperamental risk. We are also interested in how certain experiences in childhood and adolescence, such as trauma, coercive parenting, neighborhood violence, and minority status/identity, place individuals at risk for emotional difficulties later in life. We assess behavior regulation and emotion regulation using direct observation, psychophysiology, self-reports, and both structural and functional brain imaging.
Beauchaine, T. P. (2020). Family history of depression and child striatal volumes in the ABCD Study: Promise and perils of neuroimaging research with large samples. Journal of the American Academy of Child and Adolescent Psychiatry. Advance online publication.
Beauchaine, T. P., Sauder, C. L., Derbidge, C. M., & Uyeji, L. L. (2019). Self-injuring adolescent girls exhibit insular cortex volumetric abnormalities that are similar to those observed in adults with borderline personality disorder. Development and Psychopathology, 31, 1203-1212.
The Adolescent Health and Development in Context study (R01DA032371) is a large-scale, longitudinal, representative data collection effort focused on the social and spatial contexts of youth development. The project uses an innovative combination of smartphone-based GPS and ecological momentary assessment to gather real-time data on the everyday experiences of urban youth. The project is currently funded by NIDA (R01DA042080) to explore the links between exposure to violence, neural development, and substance use.
The Motivation and Cognitive Science Laboratory is dedicated to understanding how what people want (motivation) and how they think (cognition) interact to shape judgment and decision. We use a variety of cognitive, behavioral, and, more recently, neuroscientific methods, to examine why people make decisions and behave in ways that undermine their valued goals.
Stillman, P. E., Lee, H., Deng, X., Unnava , R., Cunningham, W. A., & Fujita, K. (2017). Neurological evidence for the role of construal level in future-directed thought. Social Cognitive and Affective Neuroscience, 12 , 937-947.
The Vision & Cognitive Neuroscience Lab uses perceptual and computational cognitive neuroscience techniques to investigate human visual processing. Research topics include how visual properties such as color, shape, and spatial location are perceived and coded in the brain, and how these representations are influenced by eye movements, shifts of attention, and other dynamic cognitive processes.
The MINDSET lab studies the chronic effects of traumatic brain injury and psychological stress on the brain, cognition, and risk for neurodegenerative disease. We incorporate neuroscience tools including structural T1-weighted imaging, diffusion tensor imaging, and fMRI with genetic and molecular markers to examine links between trauma and neurodegenerative disease.
Hayes, J.P., Moody, J.N., Roca, J.G., Hayes, S.M. (2020). Body mass index is associated with smaller medial temporal lobe volume in those at risk for Alzheimer's disease. NeuroImage: Clinical, 25, 102156.
Hayes, J.P., Logue, M.W., Sadeh, N., Spielberg, J.M., Verfaellie, M., Hayes, S.M. et al. (2017). Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain, 140, 813-825.
Scott M. Hayes
The Buckeye Brain Aging Lab (B-BAL) examines age-related changes in memory and the brain, variables that optimize cognitive and brain health (cardiorespiratory fitness, mobility, strength), and the neural correlates of memory in healthy and patient populations.
Hayes, S. M., Hayes, J. P., Williams, V. J., Liu, H., & Verfaellie, M. (2017). FMRI activity during associative encoding is correlated with cardiorespiratory fitness and source memory performance in older adults. Cortex, 91, 208-220. doi:10.1016/j.cortex.
Hayes, S. M., Salat, D. H., Forman, D. E., Sperling, R. A., & Verfaellie, M. (2015). Cardiorespiratory fitness is associated with white matter integrity in aging. Ann Clin Transl Neurol, 2(6), 688-698. doi:10.1002/acn3.204
Palombo, D. J., Hayes, S. M., Reid, A. G., & Verfaellie, M. (2019). Hippocampal contributions to value-based learning: Converging evidence from fMRI and amnesia. Cogn Affect Behav Neurosci, 19(3), 523-536. doi:10.3758/s13415-018-00687-8
The Hoskinson Lab aims to improve understanding of the neuroanatomical and functional substrates that contribute to cognitive, emotional, and behavioral morbidities after childhood neurologic injury. Their research integrates neuroimaging methods with assessed and observed social and emotional function to identify those at greatest risk of poor outcome. Current funded work examines the neural and behavioral consequences of traumatic brain injury, congenital heart disease, and pediatric cancer.
Wier, R., Aleksonis, H. A., … & Hoskinson, K. R. (2019). Fronto-limbic white matter microstructure, behavior, and emotion regulation in survivors of pediatric brain tumor. Journal of Neuro-Oncology, 143, 483-493.
Hoskinson, K. R., Bigler, E. D., … & Yeates, K. O. (2019). The mentalizing network and theory of mind mediate adjustment after childhood traumatic brain injury. Social Cognitive and Affective Neuroscience, 14, 1285-1295.
Aleksonis, H. A., Wier, R., … & Hoskinson, K. R. (in press). Diffusion tensor imaging of survivors of pediatric brain tumor and healthy controls: Associations with neurocognitive function. Applied Neuropsychology: Child.
The Mobility and Exercise in Neurodegenerative Disorders (MEND) lab is primarily focused on conducting research related to assessments and interventions to measure or improve balance, mobility, and fall risk in individuals with neurodegenerative disorders such as Parkinson’s disease, Huntington’s disease, multiple sclerosis, and Alzheimer’s disease. They have explored the use of innovative interventions such as video game based exercise and biofeedback delivered via application software on an iPod to improve or maintain balance and gait functions. Their research utilizes a restorative approach of using targeted interventions to improve or maintain balance and gait functions through intensive training or medication to induce neuroplastic changes rather than through compensation.
Dr. Kraemer’s laboratory is dedicated to the understanding of integrated physiology of physical function and how it mediates brain function. Using exercise stress models, we study cognition, recovery modalities, physical injury, and their effects on the brain. By better understanding stress, will allow improved coping and therapeutic strategies to effectively modulate it in people from all walks of life trying to optimize human performance.
The Krajbich Lab studies Neuroeconomics and Decision Neuroscience. Their research combines tools from psychology, neuroscience, and economics to investigate the mechanisms behind decision-making. They are particularly focused on dynamic, computational modeling. https://u.osu.edu/krajbichlab/
Marjean Kulp and Nicklaus Fogt
The goals of the ICITE study group are to compare BOLD response during convergence in those with normal binocular vision and those with poor convergence (convergence insufficiency) and also following treatment.
Andrew B. Leber
The Cognitive Control Lab aims to understand how we control behavior. The lab is especially interested in our abilities to resist distraction and suppress irrelevant information, the influences of past experience, and the factors motivating the choice of optimal vs. suboptimal control strategies.
Irons, J. L. & Leber (2020). Developing an individual profile of attentional control strategy. Current Directions in Psychological Science. Advance Online Publication https://doi.org/10.1177/0963721420924018
Leber, A. B., &, Gwinn, R. E., Hong, Y. L., & O’Toole, R. J. (2016). Implicitly learned suppression of irrelevant spatial locations. Psychonomic Bulletin & Review, 23 (6), 1873-1881. https://doi.org/10.3758/s13423-016-1065-y
Leber, A. B., Turk-Browne, N. B., & Chun, M. M. (2008). Neural predictors of moment-to-moment fluctuations in cognitive flexibility. Proceedings of the National Academy of Sciences, USA, 105 (36), 13592-13597. https://doi.org/10.1073/pnas.0805423105
Dr. Lindsey's lab studies human color vision. They use fMRI techniques to explore neurophysiological correlates of the high level representation of color appearance, categorization and memory. They are particularly interested in the role of language in mediating these representations.
Dr. Lo's study goals were to compare children who had suffered stroke with age and gender matched controls, and 1) To determine whether there are group differences in resting state connectivity for brain networks associated with social cognition; 2) To determine any correlation between resting state connectivity of these networks and performance on functional measures of social cognition.
Aleix M Martinez
The Computational Biology and Cognitive Science Lab (CBCSL) focuses on the theoretical aspects of cognitive science and neuroscience, with a particular emphasis on vision, emotion, learning and linguistics. They combine computational modeling with imaging and behavioral data to acquire a broader understanding of how the human brain functions. This includes research in machine learning and computer vision.
The Clinical Neuroscience Lab seeks to assess the efficacy of psychosocial lifestyle interventions, including physical activity and mindfulness meditation, in improving cognitive and affective functioning in clinical and healthy populations. The lab’s research utilizes resting state and task-based functional connectivity to elucidate potential mechanisms underlying change from healthy lifestyle behaviors.
Manglani, Samimy, Schirda, Nicholas, & Prakash. (2020). Effects of 4-week mindfulness training versus adaptive cognitive training on processing speed and working memory in multiple sclerosis. Neuropsychology, 34,591-604.
The Z-Lab studies Developmental Cognitive Neuroscience. We use longitudinal neuroimaging and computational modeling to investigate the developing human brain, answering questions like: What are the brain building blocks that we are born with, how do they change with maturation and experience, and can we use this information to predict the development of individual abilities later in life?
"Tracking the Roots of Reading Ability: White Matter Volume and Integrity Correlate with Phonological Awareness in Prereading and Early-Reading Kindergarten Children.” (2013). Journal of Neuroscience.
Brandon M. Turner
The Model-based Cognitive Neuroscience lab investigates how individual experiences shape one’s representations of the world, and ultimately how these representations guide behavior. To this end, a large component of the lab’s focus is on understanding how brain and behavioral data can be linked to form a more complete understanding of the mind.
Bahg, G., Sederberg, P. B., Myung, J. I., Li, X., Pitt, M. A., Lu, Z.-L., and Turner, B. M. (in press). Real-time Adaptive Design Optimization within Functional MRI Experiments. In press at Computational Brain and Behavior.
Turner, B. M., Palestro, J. J., Miletic, S., and Forstmann, B. U. (2019). Advances in techniques for imposing reciprocity in brain-behavior relations. Neuroscience and Biobehavioral Reviews, 102, 327-336.
Research in the Wagner Social Cognitive Neuroscience (CSCN) lab is aimed at understanding how cognitive representations of social knowledge are encoded in patterns of brain activity. Using a combination of functional neuroimaging, machine learning techniques and popular media (e.g., films, television), research in the lab is working towards developing methods to gain access to how individuals think and feel about the people around them. A separate line of research involves understanding the interplay between motivation, self-control and desire in order to identify neural predictors of self-regulation success and failures.
The Social Neurochemistry Lab's research is focused on how psychological factors (e.g. stress; valence weighting bias) trigger the immune system and also how the immune system can alter emotions and decision-making. They use both pharmacological (acetaminophen; ibuprofen; typhoid vaccination) and endogenous measures (e.g. C-Reactive Protein) of immune function. They are also conducting a large, longitudinal imaging study of adolescents to look at how geospatial stress exposure alters neural activity and predicts future substance use.